GLP-2 Teduglutide
33-AA analog of native human GLP-2
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| Compound | Teduglutide — GLP-2 receptor agonist |
|---|---|
| Structure | 33-AA analog of native human GLP-2 with Gly→Ala substitution at position 2 for DPP-4 resistance |
| Molecular Weight | ~3900 Da |
| Form | Lyophilized powder, sealed vial |
| Purity | ≥99% by HPLC; identity confirmed by MS |
| Storage | −20 °C lyophilized; 2–8 °C after reconstitution; avoid freeze–thaw |
| Solubility | Sterile / bacteriostatic water |
| Intended Use | In-vitro and preclinical laboratory research only |
Research Areas
Investigated in intestinal epithelial growth and repair models, gut-barrier and mucosal integrity assays, villus-length and crypt-depth studies, and short-bowel–related preclinical research. GLP-2R-mediated crypt-cell proliferation and apoptosis-inhibition pathways are standard study endpoints.